In the third study, we examined CO2 responsiveness experiment under JM-1232 at 0.3 mg/kg/min intravenously and 1 MAC sevoflurane.
Although there was some degree of female consistency in overall responsiveness between experiments 1 and 3, consistency within experiment 3 was not significant.
Female responsiveness in experiment 3 was also not positively related to the redness of a male's beak (r = −0.14, N = 85, P = 0.20; the negative sign stands for a trend towards females preferring orange).
Moreover it is not indicated what the threshold is for responsiveness in these experiments.
In fact, the response was more in line with the one observed in the 0.1 g* and 1.9 g* positions: possibly due to the sum of environmental factors causing the higher responsiveness of this experiment.
In 1979, Dickinson and Outram (5 ) conjectured that, in some experiments, scrapie responsiveness is the opposite of what one normally expects with an infection, "raising the possibility that, far from being inimical, some part of the host's immune system is essential and may even play the role of a Trojan Horse for these agents when infection occurs by a peripheral route".
As intestinal flora may affect TLR-ligand responsiveness, we performed an experiment with germ free neonate and adult mice.
The mutated plasmids were designated pTK-5103as-mut1, pTK-5103as-mut2, pTK-5103as-mut3, pTK-5103as-mut1+2 and pTK-5103as- totmut, and were tested for their PMA-responsiveness by transient transfection experiments in HeLa cells (Figure 4).
In the first part of the experiment, the responsiveness to alcohol (1.75 g/kg) per se was investigated.
The minimal role of circadian entrainment history on photoperiodic responsiveness was corroborated in Experiment #3, which employed a different method to dissociate circadian and melatonin histories.
