The responsiveness indices (effect size) for tip pinch show moderate effect sizes (0.33 and 0.58) at 12 weeks after surgery.
The overnight fever item and daytime fever item were deleted due to poor reliability and construct validity correlations (r = 0.02 and r = − 0.03 with the PGIC, respectively), and relatively small responsiveness statistics (effect sizes = − 0.92 and − 0.96, respectively).
Besides clinical responsiveness, the effect of rFVIIa should be monitored with laboratory parameters, whereas appropriate tests are discussed controversially.
The literature on responsiveness using effect sizes and other "inappropriate measures" should not be thrown away, but provides less evidence than previously thought.
Due to the limited reliability, moderate responsiveness, floor effect and large measurement error of both the pain and most of all the perception scale, found in our study and other studies it is advisable that the items in these scales (item 10-17) are used with extreme caution.
The aim of this retrospective study was to analyze the natural history of classical trigeminal neuralgia in a large cohort of patients, focusing on drug responsiveness, side effects related to CBZ and OXC, and changes in pain characteristics during the course of disease.
For the oro-cephalic responsiveness, the effects of the independent variables (olfactory stimulus, test period and mode of feeding) were assessed using a 3-way repeated-measures ANOVA.
