Non-responsive treated discs (which did not exhibit degenerated changes at 4 weeks) were excluded from the analysis.
Non-responsive treated discs (which did not exhibit degenerated MR morphology) were excluded from the analysis (PBS group; n = 7 discs, PPP group; n = 7 discs, PRP group; n = 8 discs).
It turned out to be a very good choice; the friendly and responsive staff treated us and our toddler son with down-to-earth good cheer.
HuH28 becomes responsive if treated in combination with erlotinib.
To confirm that pre-selection DP thymocytes are Hh-responsive, we treated TCRαKO DP thymocytes with recombinant (r) Shh and measured expression of the Hh target gene Ptch1.
The hypothesis that a low mitotic count would characterize non-responsive patients treated with taxanes was not supported by our results.
As shown in Figure 7A, tumor lysates of Am580-responsive mice treated with Am580 exhibited increased levels of growth arrest (p27) and differentiation (E-cadherin) markers compared to the Am580-nonresponsive tumors.
Our communities are, on the whole, more responsive and productive when treated responsibly and given responsibility about their affairs.
To confirm that high expression of RARγ correlated with lack of responsiveness to Am580, sections from untreated (control) and treated responsive and nonresponsive tumors were examined for protein levels of RARα target genes by western blotting and immunohistochemistry.
Those that are well-responsive can be cured by lower doses, those that are less responsive are (automatically) treated with higher doses.
G-C ethane cross-link formation appears to be responsible for the vast majority of the cytotoxicity in responsive tumor models treated with 90CE prodrugs and for a large proportion of the cytotoxicity of BCNU and other chloroethylnitrosoureas (CNUs).
