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Consistently with the results of the single days, AUC 2 4 of nucleosomal DNA could discriminate between the groups of patients with complete response and those who were not responsive to therapy (p = 0.042).
If these values were integrated in the area under the curve of days 2 4 (AUC 2 4) of circulating nucleosomal DNA, a significant difference between patients with complete response and those who were not responsive to therapy was observed (p = 0.042).
MRI studies of the therapeutic response to biologics have shown osteitis to be responsive to therapy with anti-TNF, B cell depleting therapy, and other biologic agents.
These response rates suggest that a subset of patients with CRPC may be responsive to therapy with ipilimumab, although none of the data reported to date have revealed specific characteristics of this subset.
That is a world full of terrorists and rogue regimes dedicated to our destruction and not responsive to therapy or social work.
Although initially responsive to therapy, indolent non-Hodgkin lymphomas (NHLs) are generally incurable.
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Compared with non-menstrual migraine attacks, MM/MRM attacks are generally longer lasting, more debilitating, more prone to recurrence, and less responsive to therapies such as triptans [9, 10].
One of the major therapeutic problems is that tumors initially responsive to chemotherapeutic approaches can progress to more aggressive forms poorly responsive to therapies.
Despite the increase in relapse, 0 of the 10 anti-RR-positive patients were non-responsive to therapy, compared to 7 of the 42 (17%) anti-RR-negative patients (p = 0.32).
Although any clinical feature may become persistent and non-responsive to therapy, the most concerning features are refractory lupus nephritis, scarring cutaneous disease and neuropsychiatric lupus (NPSLE).
The recognition that activating mutations in the KRAS gene render patients non-responsive to therapy with anti-EGFR monoclonal antibodies has resulted in the need for tumour mutation status to be ascertained before treatment.
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CEO of Professional Science Editing for Scientists @ prosciediting.com