DOI: http://dx.doi.org/10.7554/eLife.03701.008 Secondly, only the dACC and interconnected bilateral anterior insular cortex (AINS) were responsive to the three-way interaction between rule type, decision and value, with a peak in activation at −6, 32, 34 (t(19) = 5.81, p < 0.00002; Figure 4C).
In addition, the ongoing monitoring of an individual's own facial expression could distract the suppressing individual and make that person less responsive to the emotional cues of an interaction partner.
Here, we present a very different approach that also achieves the goal of improving structure quality; in this case by incorporating terms responsive to hydropathic interactions into the X-ray refinement target function using the empirical HINT (Hydropathic INTeractions) forcefield [11].
SK-OV-3 cells appear more responsive to platelet interactions, both in relation to the level and number of EMT-like gene expression changes occurring (Fig. 2b).
It remains unclear if the very tight binding in untransfected BMP2 responsive cells is due to the interaction of the ligand with both endogenously expressed type I and type II receptor chains resulting in a heterohexameric complex.
In most of the responsive cases the interaction between the modifier and the cytotoxic drug was synergistic.
The rationale of the network target concept and NIMS is to transfer the relationship among agents to the interactions among the targets or responsive gene products of agents in the context of a biological network specific for a disease or pathological process.
Viscometry, static light scattering and turbidimetry studies were performed to investigate the interaction between pH-responsive microgels consisting of methacrylic acid (MAA) and ethyl acrylate (EA) copolymers cross-linked with di-allyl phthalate (DAP) and the solvent environment.
In addition, Zap1, a yeast zinc-sensing transcription factor, also possesses a tandem CWCH2 structure in its zinc-responsive domain, where the interaction between the two ZF is required for the high affinity binding of the zinc ion (43).
Effector cell populations continue to be responsive to 4-1BB thisgering; this receptoreceptor-ligandction may to some extent substitute for the loss of signals derived by CD27 and CD28.
