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While B. bronchiseptica is fairly responsive to negative modulators, the sensitivity of B. pertussis to modulators appears to vary between isolates, which might suggest that the ability to down-modulate virulence has become dispensable for this species [16].
We also observe that the instrument tends to be more responsive to negative changes.
While Teitelbaum (25) has expressed concern that training practices and early career decisions for Ph.D.s are not responsive to negative feedback from the job markets, this is not the case for physicians.
Because the mutant Crh promoter is partially responsive to negative feedback, this may explain why plasma ACTH concentrations are lower than might be expected for a model of ACTH-driven glucocorticoid excess.
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Thus, while plasticity may operate to both negative and positive information, attention will generally be more responsive to the negative.
The TCF/LEF signature consisted of 74 genes that were responsive to dominant-negative TCF-4 (twofold cut-off) in colon cancer cells.
This indicated that this gene expression is responsive to both gram-negative and positive bacterial infection, and may be involved in the recognition of distinct types of bacteria in innate immune responses.
Overall, our study suggests that preschoolers' brains appear to be more responsive to positive feedback than to negative feedback, as reflected in increased brain electrical activity (i.e., greater P1 and PSW) to positive feedback.
Therefore, these type-1 dopamine neurons were responsive to both reward and negative signals.
Accordingly, hallucinations have traditionally been one of the main treatment targets for antipsychotic drugs and indeed the positive psychotic symptoms of schizophrenia collectively are far more responsive to these drugs than negative or other cognitive symptoms [ 8, 9].
These observations suggest that male fetuses may be more susceptible to negative influences and more responsive to positive influences.
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