Dispersions of Carbon Black, a colloidal particle of much larger diameter, characterized as a reference system, showed a different nanomorphology and were not responsive to pH modifications, due to a different dispersion mechanism.
The results obtained suggest that despite the extensive reprogramming of donor cells that occurred by the blastocyst stage, SCNT-specific errors are of a non-random nature in bovine and are not responsive to epigenetic modifications by TSA.
Perhaps components of the origin of replication complex or other replication-associated factors are responsive to the modification state of H3K4.
Sumoylation has emerged as a central regulatory post-translational modification, responsive to a variety of environmental stresses (18), which controls the function of numerous proteins and, ultimately, cell fate (36, 37).
Experimental evidence suggests that some of these DNA and histone modifications are responsive to both internal and external cues and can be rapidly activated in a context-dependent manner [ 31 38].
Photosynthetic and related plant gas exchange variables demonstrated a clear protective effect of Alethea, and our subsequent transcriptomics approach identified a number of genes responsive to Alethea application plus a modification of the salt stress response in the presence of Alethea.
We examined this hypothesis with respect to the DDR and report our findings from a large-scale antibody-based screen for histone modifications that are responsive to DNA damage.
In vivo, sumoylated PARP-1 is associated with chromatin, but the modification is not responsive to DNA damage and is not affected by PARP-1 catalytic activity.
Several subsets of genes were identified, including protein kinases, Ca2+-binding sensor proteins (CaM), genes responsive to oxidative stress, transcription factors, cell-wall modification genes and phytohormone-responsive genes.
Increased cellular H2O2 levels promote the formation of an intracellular disulfide bond thereby blocking the receptor activity, whereas the presence of Prx2 effectively prevents this oxidative modification leaving the receptor responsive to VEGFA stimulation [ 147, 148].
