They are moderately responsive to chemotherapy with different regimens showing various degrees of response in case reports/series.
The serial collection of solid tumor samples from the same patients has been extremely difficult in the clinical setting, but gastric cancer provides a unique opportunity for this purpose, since it is often initially responsive to chemotherapy and repeated endoscopies may be performed to monitor tumor response to chemotherapy.
GTN tumors are generally highly responsive to chemotherapy.
Although sensitive and responsive to chemotherapy, SCLC has an increased propensity for early metastases, with relapses being common and long-term survival rates being poor.
Background: Although childhood acute lymphoblastic leukemia (ALL) is highly responsive to chemotherapy, reliable techniques are needed to determine treatment outcome and predict impending relapse.
In light of encouraging results in mouse studies, we are now testing this approach at Memorial Sloan Kettering in patients with chronic lymphocytic leukemia and acute lymphoblastic leukemia who are no longer responsive to chemotherapy.
(The first is far less responsive to chemotherapy).
Special pathologic studies can identify subsets of patients with tumor types that are more responsive to chemotherapy.
Non-small cell lung cancer patients whose tumors have neuroendocrine (NE) features may be more responsive to chemotherapy.
Either cutting the nerve or using the toxin Botox slowed the growth of tumours or made them more responsive to chemotherapy.
It looked like a slower-growing variety, which would be less responsive to chemotherapy and more likely to be terminal.
