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In other words, complex event processing enables organizations to become responsive, to become adaptable and to become agile.
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However, a large number of HER2+ tumors are not responsive to, or become resistant to, trastuzumab-based therapy, and thus more effective therapies targeting HER2 are needed.
However, a consistent number of HER2+ tumors are not responsive to, or become resistant to, trastuzumab-based therapy, suggesting the need to develop additional novel therapies targeting HER2 [ 3].
Five out of the seven individuals who were responsive to MCT became unresponsive, however the remaining two responsive individuals had a lower PD15 compared to their individual PD15 at day 0 and day 7 (data not shown).
Still, we still somehow need to become responsive to the earth.
These findings suggest that organizer-derived signals other than BMP inhibitors are required for epiblast cells to become responsive to BMP antagonism.
Thus, stimulation of LP DC with TLR ligands induces phenotypic maturation and allows the cells to become responsive to CCR7 ligands.
Introduction of the exogenous mPRα cDNA into these cells caused cell proliferation, but not EMT, to become responsive to P4 treatment.
These C-fibers are inexcitable by noxious mechanical or thermal stimuli in normal tissue but inflammation sensitizes them to become responsive to stimuli.
One potential strategy could be to convert an endocrine nonresponsive tumour to become responsive to oestrogen-induced apoptosis by blocking the survival pathways with the expanding list of tyrosine kinase inhibitors and antibodies that block cell surface signalling.
Since gp130 is ubiquitously expressed, sIL-6Rα offers the opportunity to cells that do not express IL-6Rα to become responsive to IL-6, a phenomenon called trans-signaling.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com