Sentence examples for responsive subgroups from inspiring English sources
Improved scientific understanding of the biological characteristics of poorly responsive subgroups will facilitate the design of novel biologically rational combinations.
One feature distinguishing the two more responsive subgroups from the two more stable subgroups was the MPH dose at study start.
Another clinically significant result reported by Wattmo and colleagues is the clear observation of an initial improvement in the responsive subgroups at 6 months, followed by nearly parallel trajectories of decline over the next 30 months.
Discrimination against entire subgroups could also occur if, for example, genetic variants were found to correlate with a more favorable vaccine or treatment response, but only in certain ethnic groups; also, drug development might focus on these 'more responsive' subgroups.
Clearly, prescribing drugs only to a responsive subgroup of patients would improve the cost-effectiveness of the treatment.
Due to the fact that the premedication in the more-responsive subgroups was lower than that in the less-responsive subgroups, the relative increase in MPH dosage in these groups was the highest after the medication switch.
However, more-responsive versus low-response subgroups could not be distinguished by the prescribed MR-MPH doses during the observation period.
Cluster 3 (red) was highly enriched with marker genes for the androgen-responsive subgroup of ER- breast cancer described by Doane et al. [ 40].
On a descriptive level, children in the more-responsive groups were treated less intensively prior to study start; statistical analysis confirmed that lower MPH dose before medication switch was linked to a higher probability of falling into a more-responsive subgroup.
Diabetes-specific instruments, such as the ADDQoL, are more sensitive to change and responsive to subgroup differences than a generic instrument [ 15].
Diabetes-specific instruments do not allow comparison with other conditions, but they are likely to be "more sensitive to change and responsive to subgroup differences than a generic instrument" [ 47].
