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These 36 cell lines were either responsive ("responsive" was defined as an IC50 value of less than 1 μM) to both HCI-2184 and HCI-2389 or nonresponsive to either of the two inhibitors selected for the proteasome activity assay.
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According to the 2005 St Gallen guidelines (Goldhirsch et al, 2005), endocrine responsiveness (responsive, uncertain, or non-responsive) and recurrence risk (low, intermediate, or high) were assessed.
More individual response failures in responsive SPNs and non-responsive neurons are observed at the younger ages.
First revision is that endocrine responsiveness is divided into responsive, non-responsive, and uncertain classifications.
The tree level reflected the phenotypic plasticity of each genotype in response to water availability (1 = highly responsive, non-significant = non responsive).
Abiotic stress responsive transcripts encoding salt responsive protein 2 (DMP400000646), early response to dehydration 7 (ERD 7 DMP400010986) associated with dehydration, and transcription factor ZPT2-13 (DMP400027220) were also induced.
A similar elevated expression trend was also observed for genes involved in ethylene response including an ethylene inducible protein (SGN-U214488) and ethylene responsive element (ethylene responsive protease inhibitor I: SGN-U217278, EREBP: SGN-U213917).
NAC TFs manipulate plant stress responses by activating other genes encoding R2R3-MYB TF, amylase, cold responsive protein, dehydration responsive proteins, GST, and late embryogenesis abundant (LEA) proteins [ 56].
Even when cell lines were classified into IGF-1 responsive and non-responsive classes (independently of the magnitude of the response), no enrichment was observed with IGF1R levels.
First, single units with statistically significant responses to at least one stimulus were classified in a winner-take-all manner as 'conspecific responsive' or 'predator responsive' based on the magnitude of stimulus-driven responses.
One learning was that the complexity of having a mixed site of responsive and non-responsive pages should not be underestimated.
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