Whereas the pathological consequences of myofibroblast occurrence are of great interest for physicians, their mechano-responsive features render them attractive for physicists and bioengineers.
The positively charged cationic hydrogel microparticles were embedded/dispersed into another hydrogel matrix to render responsive behavior to a non-responsive matrix.
In its original configuration, an artificial promoter was rendered responsive to a chimaeric transactivator (tTA, composed of the repressor (TetR) fused to the VP16 activation domain), by linking the seven repeats of the Tet operator sequence to the minimal promoter elements of the human cytomegalovirus immediate early gene (CMV-IE) promoter.
Carvedilol has been shown to restore the effects of IPC in a rat model of coronary artery stenosis (Oikawa et al., 2008), and humans resistant to IPC were rendered responsive to IPC by pre-treatment with enalaprilat (Ungi et al., 2008).
It's a vision that renders government less responsive and less responsible to its citizens.
For this purpose, we developed a dual (thermo- and pH-) responsive nanotherapeutic composite system rendering a combinational therapy of hyperthermia mediated drug delivery.
D1 and D2 dopamine receptors are present on endothelial cells, rendering them responsive to dopamine.
Tumor cells frequently express the receptor for IL-6, thus rendering them responsive to autocrine and/or paracrine IL-6-mediated stimulation [ 13, 16].
However, interventions in post-conflict zones frequently are not responsive to local realities, rendering them ill-equipped to foster both local strengths and participation in the social repair process [ 1, 2].
Furthermore, it might benefit the development of DC vaccines against cancers and autoimmune diseases, as manipulating DCs in vitro and rendering them responsive to tumor antigens may lead to tumor regression [ 10].
