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By targeting the messages to subgroups known to be most responsive, program costs could be reduced by over 50% with only a 20% reduction in the treatment effect.
This coordinated and environmentally responsive program of meristematic differentiation and tissue patterning involves multiple developmental processes with interacting regulatory mechanisms (reviewed in [ 7, 8, 4]).
Because the CMAP database contains profiles from a large collection of human cancer cell lines containing information on how cells respond to chemical stimulations, it can be used to test the hypothesis that the apoptosis pathway might be a major responsive program to drug perturbations in cancer cells.
The module eigengene value significantly correlated with known maker genes for salt [ 33, 37, 38] (ATPearsonearson cor = 0.68, p = 7 × 10-10) and osmotic stress (KIN1, cor = 0.74 p = 3.5 × 10-12; cor78, cor = 0.64, p = 1 × 10-8) [ 33, 39, 40], further suggesting a role for the turquoise module in the dehydration responsive program.
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Our school's balanced and responsive programs go way beyond strict discipline.
The use of ToC models, plus the addition of ET, is a way to encourage individual and organizational learning and adaptive management that supports more reflective and responsive programming.
Such an informed approach has the potential for development of more appropriate and culturally responsive programs being implemented in ways that lead to the desired impacts, as well as to lead to evaluation approaches that support effective solutions to intransigent social problems.
We are speaking to development partners to inform the direction of their investment; to governments to enable them to rethink their strategies as they relate to young people's sexual and reproductive health, and to fellow youth to act together in advocating for more responsive programs and policies on sexual and reproductive health for young people.
UNICEF continues to welcome thematic humanitarian funds as they allow more responsive programming, based on country and global priorities.
Child protection actors now accept the need to shift away from issue-specific, responsive programming towards a systems approach that includes a strong focus on prevention.
The green module, for example, was almost entirely unique to the heat stress pathway and was, in fact, enriched with genes known to participate in heat responsive programs.
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