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Repeated exposure to the same stimulus causes neurons coding non-specific stimulus features to drop out of the responsive pool, while neurons tuned optimally to the stimulus continue their activity [40], [41], [42].
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Surprisingly, we found very few of these mRNAs in our insulin-responsive pool of transcripts recruited to cardiomyocyte polysomes (Additional files 6 and 8).
CD8+ T lymphocytes were then stimulated for 10 days with the most responsive peptide pool to obtain specific CTL.
26 It was suggested that the benefit of DHEA treatment would be most effective if it was supplemented for at least 3 months, which is equal to the time needed to affect the gonadotropin-responsive follicle pool.
Although definitive markers for articular cartilage progenitors are lacking [ 19], our observation that Mig-6-deficient articular cartilage contains a population of cells which are highly proliferative and which express Notch1, Sox9, SZP and GDF-5 suggests the existence of an endogenous EGFR-responsive progenitor cell pool in articular cartilage.
It has been previously shown that the SC pool is responsive to exercise-induced muscle damage [12] [14]; however, the regulation of this response remains poorly understood.
The possibility of identifying a pool of responsive academics or resource persons to help support specific tasks (such as protocol review or statistical analysis) could also be considered.
Within the pool of NDGA responsive kinetochore proteins there appears to be two distinct types of proteins; those that only accumulate at the spindle poles following NDGA treatment when the checkpoint is active (e.g. Mad2) and those that accumulate throughout mitosis (e.g. hZW10).
Spinal locomotor pools are highly responsive to phasic segmental sensory inputs and show evidence of learning during step training [ 11].
The influence of hormonal environment during the critical period of mammary gland development thus determines the future carcinogenesis process and the pool of hormone-responsive epithelial cells (Nandi et al, 1995).
Using sequential enrichment, deep sequencing and a bioinformatics pipeline, candidate responsive SynCREs were identified within a pool of constitutively active DNA elements and further validated.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com