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In fact, the distance a given group of treated patients moved towards the normal controls was proportional to their level of response, with fully responsive patients moving closer to healthy controls than partially responsive patients (Fig. 7).
Here's a detailed comparison of the five responsive patients, following the instruction to imagine playing tennis (Owen, 2013).
Less responsive patients are those with more advanced fibrotic changes, but such cases have not been well defined.
Better techniques to predict response, determine residual tumor burden before operation, and greater willingness to attempt BCS in responsive patients could additionally improve the rate of successful BCS.
Responsive patients are <65 years old and have a higher frequency of severe headache and a lower share of mild headache.
In other words, patients who were proven to be not fluid responsive continued to receive the same amount of subsequent fluid boluses as did fluid responsive patients.
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For most sapropterin-responsive patients, the benefits of treatment are such that long-term therapy with sapropterin should be maintained.
Small-bowel villous atrophy occurs in other enteropathies and non-responsive patients are often seronegative.
Most sapropterin-responsive patients have a rapid decline in blood PHE level, but occasionally a delay of 2 4 weeks is seen.
Medication-responsive patients may cease to respond over the long term if they cycle on and off the medications; with each episode, there is a ten-per-cent increase in the risk that the depression will become chronic.
The PRR was determined in 22 non-responsive patients.
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