A series of experiments were performed to further evaluate the apparent copper responsive down-regulation (mid-exponential) and rebound (stationary phase) of SOD activity in K. radiotolerans.
We did not pursue further analysis of the BAR-1 responsive down-regulated genes.
Remarkably, five out of nine glucose-responsive down-regulated genes in controls have a documented role in immune cell-induced cytoxicity: chloride intracellular channel 3 (CLIC3), killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 (KIR2DL4), perforin 1 (PRF1), Granzym B (GZMB) and granulysin (GNLY).
Similarly to the grapevine SDH Class I gene, SDH Class II transcription was also stress responsive, being down-regulated during the heat stress recovery of grapevine leaves and up-regulated during exposure to UV-C light irradiation (Additional file 12: Table S3).
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I rarely hit the wrong spot and it's responsive to holding down as well.
The predominance of non-responsive or down-regulated transcripts was evident within almost every category of ROS-scavenging enzymes, except for alternative oxidase, ferritin, and monodehydroascorbate reductase, in which all NaCl-responsive transcripts were induced.
Yet, these methods cannot recognize bidirectionally (up and down) responsive pathways.
Among the several categories of iron deprivation responsive genes, the down regulation of calcineurin signaling genes including HSP90, CMP1 and CRZ1 was noteworthy.
Outcomes measuring links higher up this theoretical chain are likely to be more responsive than links further down.
Part of the Ultrabook concept is getting really thin, really responsive systems down into the mainstream, he says.
