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Platforms should provide scalable, incredibly fast and responsive database and workflow systems.
DocumentDB has been available in multiple data centers across the world, but it looks like you can now take advantage of that by building a very responsive database spread across multiple data centers.
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Genes with the greatest increase in expression in mammary tissue of soy-fed mice compared to the casein-fed mice were Pgr and Areg, both of which are regulated by ER signalling (Dragon Estrogen Responsive Genes Database [ERGDB] found at datam.i2r.a-star.edu.sg/ergdbV2/).sg/ergdbV2/
One thousand base pairs (bps) of the TF promoter sequences retrieved from Phytozome (version 9.1) were subjected to CRE analysis through DNA Pattern Search [ 55] by referring to the literature [ 56, 57] and the Stress Responsive Transcription Factor Database (STIFDB) [ 58].
The Abiotic stress related data was obtained from STIFDB (Stress Responsive Transcription Factor Database) (http://caps.ncbs.res.in/stifdb) and genes related to drought, salt and cold were retrieved [ 58].
Stress-related genes were mapped using BLASTx against the tomato proteome in the Stress Responsive Transcription Factor Database (STIFDB) [ 76], and annotations were assigned to the corresponding representative tobacco contig.
Stress resistance genes and protein sequences of Arabidopsis thaliana proteins related to salinity, drought, and freezing tolerance were downloaded from the stress responsive transcription factor database [ 26– 28] (STIFDB; http://caps.ncbs.res.in/stifdb2/) and compared with the G. sinensis unigene library to search for homologous sequences potentially possessing the same functions in G. sinensis.
The HSF binding cis-regulatory element (HSE) 'GAANNTTC' and 'TTCNNGAA' were obtained from Stress Responsive Transcription Factor Database (STIFDB V2.0) [ 114], and the DREB binding cis- regulatory element (DRE) '(A/G/T)(A/G CCGACN(A/T)' was obtained from Arabidopsis Gene Regulatory Information Server (AGRIS) [ 115].
The Stress-Responsive Transcription Factor DataBase (STIFDB) is as well a collection of abiotic and biotic stress responsive genes from Arabidopsis and Oryza sativa (rice) including the possibility to identify putative binding sites in the promoters of these genes (10, 11).
Stress-responsive TranscrIption Factor DataBase (STIFDB) provides information related to Arabidopsis genes up-regulated during abiotic stress together with putative TF-binding sites (14).
This has been confirmed in three distinct predictive databases: two responsive elements, with a confidence of prediction higher than 90%, suggests that Th is a potential target of p73.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com