Depending on the valency of the electron-rich guest moieties (Np or Azo), either SNPs with a UV-responsive shell or a UV-responsive core were formed by assembling SNPs using a mixture of Azo and Np bearing guest molecules.
The transcriptional profiles of the genes comprising the 5-genome FeHm-responsive core were examined in HI1722 by Q-PCR.
A previous iteration of the FeHm-responsive core modulon of H. influenzae was based on microarray analyses of 3 isolates [ 25].
In summary, our analysis of the RUNX1/ETO-responsive core transcriptional network in t(8 21) cells highlights the predominantly repressive role of RUNX1/ETO within this network.
It would appear from the responses to phase-shifting light-dark cycles, considering the two-process model of sleep-wake control, that the more-directly-light-responsive core is associated better with the homeostatic aspect of sleep-wake regulation, whereas the shell is better associated with the circadian modulation of sleep wake.
Here, the core shell particle structure enables the physical and compositional segregation of particle functions into an endosome-disrupting pH-responsive core and a shell whose composition could be separately tuned to facilitate particle targeting, cell binding, and/or drug binding.
To define the RUNX1/ETO-responsive core transcriptional network and monitor dynamic changes associated with alterations in RUNX1/ETO status, we utilized Kasumi-1 cells, which represent a well characterized and widely used model system for t(8 21) AML (Ben-Ami et al., 2013; Martens et al., 2012; Ptasinska et al., 2012; Sun et al., 2013).
After that, NIPAAm was polymerized from the vinyl double bonds for fabricating the thermo and pH-responsive core-crosslinked nanogels.
Herein, a kind of multi-responsive core-crosslinked poly (thiolether ester) micelles was facilely prepared for reactive oxygen species (ROS), acid and reduction sensitive drug delivery.
