Thus, another feature may be responsible for paternal X-inactivation, for example, the presence of paternally specific histones or protamines.
It has therefore been suggested that the incorporation of sequences from the CR of a standard M genome into an F genome could be responsible for the paternal transmission route of the recombinant mtDNA genome [18], [30], [39], [47], [48].
Alternatively, one or more of the 700 mis-regulated genes could be responsible for modifying paternal chromatin.
Either scenario indicates that neither DNA methylation nor Airn expression is responsible for silencing paternal Igf2r in the epiblast.
In contrast, in Family 6, where surveillance led to a widely agreed perception that the paternal clan was responsible for the condition, this attribution of cause was not associated with blaming in the same way.
But what selective factor(s) is responsible for the evolution of this paternal-effect?
In Pakistani culture, it is customary for the paternal family to be more responsible for their children and grandchildren than the maternal side, said Hamida Amanat, director of education at the Jam-e-Masjid Jam-e-Masjid Jam-e-Masjid Islamic Center
By contrast, demethylation is better supported by OR-linked architectures, which may explain the difficulty in identifying the factor(s) responsible for the active demethylation of the paternal genome following fertilization.
Alongside him, Cody is consumed first with guilt over the paternal flit for which he feels responsible, and then with jealousy of a brother you'd think it hard to want to compete with, but whose girlfriend he reflexively covets, steals and marries.
Diminished IGF2 expression, through ICR1 hypomethylation and subsequent CTCF binding and IGF2 enhancer blocking on the paternal allele, is thought to be responsible for the low birth weight and poor post-natal growth observed in SRS patients.
