Cells therefore utilize a DNA damage response pathway that is responsible for sensing, reacting to and repairing damaged DNA.
Toll-like receptor signaling is responsible for sensing pathogens and prompting cellular immune responses.
It is possible that the HK4 histidine kinase, which possesses a predicted signal peptide that would target it to the membrane, is the protein responsible for sensing environmental cues and inducing a response in the CtrA starvation degradation pathway, via PhyR (Figure 8).
PRRs are directly responsible for sensing the presence of pathogens and activating innate immune responses and are also important for subsequent acquired immunity [ 3].
In C. elegans, in the presence of food, response to 100% octanol is primarily mediated by the ASH neuron, and in the absence of food ASH, ADL, and AWB neurons are responsible for sensing 100% octanol, suggesting that feeding status of the animal affects response to 1-octanol in C. elegans [ 40].
JQ1 inhibits a family of proteins responsible for sensing acetyl groups on histones.
Instead, they are responsible for sensing nutrients and maintaining the balance of hormones essential in metabolic processes.
This article from New Scientist describes how people from Kenya and Cameroon show a striking amount of diversity in a gene responsible for sensing bitter tastes.
FixL proteins are bacterial heme-containing signal transduction proteins responsible for sensing the O2 concentration in the organism's environment.
Focusing on Sema3A-regulated neuron migration and neurite repellence, we then examined specific signaling pathways related to this cue and tried to dissect the signals that are responsible for sensing the Sema3A gradient steepness in different cellular programs.
Although we cannot draw a definitive conclusion about STK11's role in the steepness-dependent regulation of axonal repellence, this experiment, at least, suggested that STK11 is not responsible for sensing the steepness variation of Sema3A gradient during neuronal migration.
