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Thus, different related strains of MHV may induce demyelination via unique mechanisms, and it is likely that in the absence of an intact immune response, CNS infection with some strains of MHV is responsible for onset of axonal loss and demyelination, possibly through direct destruction of CNS cells [ 31].
Local disequilibria are predicted which are shown to be responsible for onset of interfacial and bulk instabilities.
Currently, there is very little knowledge available as to how DNA methylation controls the phenotype of hepatic stellate cell (HSC), the key cell type responsible for onset and progression of liver fibrosis.
It is generally recognized that PrPsc itself is the infectious agent responsible for onset of disease [2].
The distribution of causes responsible for onset of mechanical ventilation was not different in the two groups.
There has been conception that two distinct mechanisms are responsible for onset of endometrial carcinoma: endometrial carcinoma occurring in complex hyperplasia and endometrial carcinoma occurring ab initio in nonhyperplastic endometrium (de novo carcinoma) [ 1, 2].
Similar(54)
13 The investigation for factors responsible for obesity onset and response to antiobesity treatments started in the early 1960s, 16, 17 and the number of studies in this field has multiplied over the years.
If the membrane-peptide interactions are indeed responsible for the onset of the cascade of toxic responses leading to cell death, then mutations in Aβ leading to early onset cases of AD should show considerably more pronounced interaction with membranes.
Ino4p; a transcription factor required for de-repression of inositol-choline-regulated genes involved in phospholipid synthesis was responsible for this onset of a late response in the upper down-regulated branch.
PNS was suggested to affect vulnerability or resilience to the onset of stress-related psychopathological conditions by influencing epigenetic mechanisms responsible for the onset of these phenotypes [ 29, 30].
We investigated the relationship between CACS, and the redox-related genes and the genes associated with the onset of T2D to clarify the role of these genes in the mechanisms responsible for the onset of atherosclerosis in T2D.
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