Sentence examples for responsible for augmented from inspiring English sources

This increased activation of FOXO1 is responsible for augmented transcription of the MTP gene [ 66].

Therefore, it is believed that reducing the levels of inducible NO synthase (the enzyme responsible for augmented production of NO) not only may reduce the symptoms but also is likely to slow disease progression, allowing this approach to tackle two targets simultaneously.

To identify the isoform responsible for the augmented fluorescent response in mutant mice we used specific NOS inhibitors.

EWS/WT1 −KTS) activated the P3 promoter to a similar level (5-fold) as the 2-kb P1 promoter (6-fold), indicating that the removal of negative elements in the 5' upstream region (−1450 to −915) of the human ENT4 promoter may be responsible for the augmented activation of the P2 promoter by EWS/WT1 −KTS).

Therefore, we propose there should be other mechanisms are responsible for the augmented pro-inflammatory effects in castrated mice, rather than flutamide treatment.

These data suggest that the upregulation of CD150 by LMP1 is responsible for the augmented susceptibility to MV-induced cytolytic activities in B lymphoma cells.

The authors elegantly utilise a series of neutralisation treatments to mechanistically dissect the molecular pathway responsible for the augmented metastatic phenotype described upon cessation of anti-CCL2 therapy.

Recent evidence demonstrates that insulin inhibits the synthesis of endocannabinoids and that fat-specific insulin resistance may be responsible for the augmented plasma endocannabinoid levels found in insulin-resistant states.

However, this study was not able to detect a significantly elevated level of IL-13 in patients with Sch-PAH, maybe because either a larger sample size is necessary or an alteration in the IL-13 receptors is responsible for the augmented IL-13 signaling found in animal models.

19 Recently, increased expression of TLR3, and to a lesser extent TLR4, has been described in MS-circulating cells and it has been reported to be responsible for increased innate immune response activation along with augmented production of CXCL10.

Interestingly, this NF2 KO phenotype was completely prevented in mice that were also haplo-deficient for Yap, indicating that augmented Yap activity is responsible for this pathology [99].