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These responses were maintained in the presence of pro-inflammatory cytokines that might be encountered in the diseased brain.
However, levels of both mucosal and systemic OVA-specific antibody responses were maintained.
A long-term memory study of 250 days revealed that the antibody responses were maintained over time which is essential for a TBV.
The median time to first response was 1.2 months (95% CI 0.7 1.4); responses were maintained and generally deepened over time (Fig. 3a, b).
Strong responses were maintained in 5 of 7 donors (H3, H5, H7, H13, and H15) in response to rAsp f3.
Responses were maintained in 9 of 13 patients (69%) at 22 weeks after the last booster (week 29, Figure 3).
Similar(27)
These results indicate that, in the developing organism, beta-AR-mediated cell signaling responses are maintained in the face of receptor downregulation through heterologous induction of downstream signaling elements.
The ability to mount these tailored responses is maintained in the body by "memory cells".
Importantly, these higher antigen specific responses are maintained at a significantly higher level than in the BCG alone arm for at least 24 weeks after vaccination.
Surprisingly, lack of TLR-dependent responses was maintained over 4 months of differentiation of hESC, in cultures which included cardiomyocytes and endothelial cells.
It is currently unknown how long these antibody responses are maintained in nasal mucus.
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