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Identification of specific immune responses responsible for pathogen protection enables vaccine development and provides insights into host defenses against pathogens and the immunological mechanisms that most effectively fight infection.
Because induction of neutralizing antibodies is a significant factor in protection from homologous viral challenge, we compared the humoral immune responses responsible for the rapid virus clearance.
Taken together, these data demonstrate that HVEM-mediated stimulatory signals are necessary to promote the activation of innate immune responses responsible for disease induction.
Repopulation of tumor cells is one of the most common radiobiological responses responsible for the failure of IR.
Radiation-induced DNA damage initiates a complex series of overlapping responses responsible for the maintenance of genome integrity.
The YAP1 transcription factor is one of the most important determinants of oxidative stress responses, responsible for transcriptional activation of oxidative stress-associated genes in fungi [ 12].
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Rel proteins in bacteria synthesize the signal molecules (p ppGpp that trigger the Stringent Response, responsible for bacterial survival.
Shirin Peykar joined Univision Communication, New York, in a new role, vice president for direct response, responsible for building and overseeing the direct response operation.
Immunosuppressants and immunomodulators are designed to regulate excessive immune response responsible for inflammatory lesions and are prescribed more and more in internal medicine.
FcγR polymorphisms, together with other genetic and environmental factors, dictate susceptibility to disease by altering the humoral response to lupus autoantigens, as well as by modifying the inflammatory response responsible for end-organ damage.
Such findings provided a strong rationale for the development of new therapeutic approaches based on the modulation of the dysregulated immune response responsible for organ failures during sepsis.
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