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Here we performed a systematic comparison between ON responses, OFF responses and impulsive responses to tactile stimuli in the same population of thalamocortical neurons.
With his earthy, limber voice, Mr. Wilson crooned husky lines and climbed to exultant high notes, bounced responses off his backup singers or tossed off breezy scat phrases.
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Experiments and analyses focused on the responses of OFF midget cells over a range of eccentricities.
Collectively, these efforts open up exciting new therapeutic avenues but could also augment the inherent risks of RNAi technology, including immune responses, off-targeting, and oversaturation of endogenous pathways.
Tapalian et al. reported 12 (71%) of 17 patients maintained responses off-therapy for at least 16 weeks (range 16 56 weeks) [7].
The temptation is to write Debbie's response off to resentment (Debbie's ex-husband cheated on her with Ruth), selfishness, naïveté or internalized sexism.
If you find yourself saying, "Great idea," and following it with "But," or "However," try cutting your response off at "idea".
Plus, the more we keep the fight-or-flight stress response off, the fewer stress-related health issues -- like high blood pressure, chest pains, muscle aches, autoimmune diseases -- we will likely suffer from.
ON responses and OFF responses were compared within cells, using paired t-tests.
We also tested the correlations in magnitude and latency between ON responses and OFF responses using the Pearson correlation coefficient.
The photopic long-flash ERG showed severely reduced ON response and normal OFF response.
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CEO of Professional Science Editing for Scientists @ prosciediting.com