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As component mode synthesis (CMS) is adopted in order-reduced modeling, we then utilize the improved response variation prediction on modal characteristics to update the CMS model to facilitate the efficient probabilistic analysis of any responses of concern.
On the other hand, the systemic dose of chloroform, which depends upon the magnitude of the external dose and its rate of delivery to the systemic circulation, provides a clear biological threshold for the responses of concern.
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From the conventional geotechnical design, it was found that the differential settlement controlled the final design and was considered as the response of concern in the optimization procedure.
The maximum wall deflection induced by the excavation was chosen as the response of concern in the design and was computed using a finite element analysis model based upon the beam-on-elastic-foundation theory.
The key event of generation of the cytotoxic metabolite (phosgene) is rate limiting, in that the location of the threshold for the response of concern, the shape of the overall dose-response curve, and the magnitude of the ultimate response will depend upon the levels of the causative agent that are produced, which in turn will depend upon the levels of expression of CYP2E1.
Interpreting MOEs in the context of risk assessment and risk management takes into account such factors as the slope of the dose response relationship in the observable range, type of effect, mode of action, nature and extent of associated uncertainties, and human variation in susceptibility to the response of concern (Risk Commission 1997).
Instead, agency officials assisted a voluntary, industry-led response, out of concern that regulation "could have had negative financial impacts on the swine industry," according to GAO.
Responses for level of concern were combined into three categories: extremely concerned, moderately concerned and not concerned/no opinion.
Celebrated Australian novelist Tim Winton is bemused by the cultural transformation that is revealed by responses to expressions of concern about growing inequality: invariably, a retaliatory accusation of a "nostalgia for Stalin".
The effect of BAFF blockade on anti-bacterial responses is clearly of concern for patients with SLE, who are prone to infections with encapsulated organisms.
In addition, the laborious work of computing conditional probabilities as presented in the main part of analysis has yielded specific and practical understandings about under which conditions a particular response of primary concern will take place.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com