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Calibration curves of catechol and p-cresol showed good linear response with concentration in the micromolar range, and detection limits of 41 and 63 nM were found for catechol and p-cresol, respectively.
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Surprisingly, AEBSF exerted a biphasic response with concentrations <300 µM increasing the signal (EC50 = 30 µM) and higher concentrations being inhibitory (IC50 = 0.42 mM).
Pharmacological responses with concentration up to 10−10 mol/L are explained using sound theoretical models, such as substrate enzyme or drug receptor interactions; growth factors and microelements have effects at lower concentrations (usually in the range 10−10/10−20), but dose effect relationships are usually apparent.
PND15 normal pups showed a biphasic pain response with a concentration of 2% formalin injection.
Moreover, MQCM sensors show approximately linear frequency shift response with analyte concentration.
The magnetic and mechanical properties of the metal-polymer composite have been subject to experimental study that has shown the non-monotonic increase of the composite magnetodeformational response with particles concentration rise in polymer matrix.
Titration of B/BR/08 rHA on immobilized fetuin suggests the receptors are saturated at rHA concentrations >40 μg/ml, but that there is good linearity of the response with increasing concentrations between 2.5-20 2.5-20
With alphacypermethrin, there was no statistical significance in directional movement or increase in response with increasing concentrations (Fig 2B).
Softening displayed dose dependent response, with lower concentrations of propylene showing reduced softening.
Although most fish follow a conserved pattern of stress response, with increased concentrations of cortisol, each species presents specificities in the cell response and stress tolerance.
This contrasted with NGAL, which displayed a quicker response with different concentrations in the AKI compared with the non-AKI patients, starting at 24 hours prior to the AKI presentation time (P = 0.0005).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com