Recent reports revealed that a Th2 response is predominant in cancer patients (Pellegrini et al, 1996; Vita et al, 1999; Sheu et al, 2001).
In contrast, a significant increase in susceptibility to nonlethal Plasmodium was observed when mice were coinfected with Plasmodium in the late stages of helminthic infection, when the Th2-type immune response is predominant.
Our data suggest that local T-helper-2 (TH2) cytokine responses are predominant in the CSF of patients with EOMA.
Among innate immune cells, neutrophils are the most rapid and predominant cell type transmigrating into CF airways, while in adaptive immunity, T-helper cell type 2 (Th2) and Th17 cell responses are predominant [16], while regulatory T cell responses are impaired [18].
In IM immunization, the serum IgG responses were dose related and the Th1 responses were predominant as shown by the isotype profile before and post-challenge and the cytokine data.
In the presence of exogenous ligand, the occupancy of PPARβ/δ observed for type III response genes was predominant near the TSS but there was a shift in binding towards the region upstream of the TSS compared to the occupancy of PPARβ/δ observed without exogenous ligand.
In our study we noted that immune response was the predominant response at dose 10 cGy at 3 h.
T cell specificity also differed - in B10.Q mice there was predominant response to the glycosylated form of the CII259-273 epitope while in B10.DR4.Ncf1*/* mice immunodominant was the native and the hydroxylated form of the epitope.
They reported a late positive component in response to infrequent stimuli that was predominant in the front-central area, rather than the MMN-like component observed in the present study, and argued its consistency with the P3 component in human.
Moreover, similarly to that observed for α1β2γ2 receptors (although to a lesser extent), the weight of the fast component (A1) in responses mediated by α3β2γ2 channels was predominant with respect to A2 and A3 (0.47 ± 0.03, 0.29 ± 0.02 and 0.24 ± 0.02, respectively, n = 9, Fig. 3B).
