Moreover, our recent data suggest that the recall response is comprised of temporally distinct phases that involve different subpopulations of memory T cells.
However, we have found that virtually the entire peripheral blood lymphocyte (PBL) ASC response is comprised of plasmablasts, while the trout plasma cell response resides within the anterior kidney.
The insect immune response is comprised of cellular and humoral components.
As the overall response is comprised of transient and steady-state features, we next examine these two aspects individually.
Essentially the response is comprised of two regions: (a) a broad response from 300 to 475 nm and (b) a strong narrow exciton band peaking at 521 nm [with full width at half-height (fwhm) = 20 nm].
C. pasteurianum was found to exert a homeoviscous response that was comprised of an increase lipid tail length and a decrease in the percentage of unsaturated fatty acids with increasing n-butanol challenge.
Similar to the CD4+ T cell response, immunization with the HA DNA vaccine alone elicited a HA-specific CD8+ T cell response in the blood that was comprised almost entirely of mono-functional T cells expressing either IFN-γ or IL-2 (38% and 44%, respectively; Figure 6H).
Immunization with the HA DNA vaccine alone induced a HA-specific CD4+ T cell response in the blood that was comprised almost entirely of mono-functional T cells expressing either IFN-γ or IL-2 (43% and 33%, respectively; Figure 6H).
Figure 6G shows that immunization with the HA DNA vaccine alone induced a HA-specific CD4+ T cell response in the lung that was comprised almost entirely of T cells expressing a single cytokine (59%), with an almost equal distribution of cells expressing IFN-γ, TNF-α, or IL-2.
The pie charts and bar graphs provide finer details illustrating that nearly one-half of the rectal response in patients not on ART was comprised of polyfunctional cells capable of 3, 4, or 5 responses simultaneously.
