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This vaccine has shown that it can break tolerance of the PSA, and its administration directly into a tumor enables the affected tumor cells to act as antigen-presenting cells activating new T-cells, and broadening the immune response to recognize and kill tumor.
When this rate of change is too slow for the heat shock response to recognize and repair the damage, system failure in the form of protein folding diseases and aging is possible [16].
TLRs act mainly to initiate an innate immune response against invading microbes and, through dendritic cells, activate the adaptive immune response to recognize specific pathogens [ 180].
(5) Thus, enlisting the host response to recognize poorly immunogenic tumors, and altering the immunologic intratumoral microenvironment may be beneficial for the treatment of cancer.
This would require establishing a government focal point to coordinate the overall response to recognize violence against children, register the cases, refer the children to appropriate services and be fully accountable in its response to these cases.
DCVax-L uses patient-derived tumor and healthy dendritic cell tissues to educate the innate immune response to recognize GBM tissue for elimination and has been shown to be safe (Yu et al, 2004) (Prins et al, 2011).
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Certainly the right response to recognizing this wrong is to have the WTO cease that unjust behavior.
These policy-led interventions and funding support had in turn been a response to recognized NHS nursing shortages in the late 1990s.
The BMC series was one initiative from BioMed Central in response to recognizing that the quantity of results and data being generated was too much for conventional systems of publication to deal with.
However, the extent of success among such DC vaccine-based approaches will clearly depend upon the ability of LMP2A-CTL responses to recognize weakly immunogenic tumors that are possibly undergoing immunoediting to escape detection.
The humane response is to recognize and treat both their grief and depression.
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