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Through trainings and advocacy, the pilot team articulated the need for a more comprehensive response targeting the three key components of MHM (information, supplies, infrastructure, see Fig. 1).
Since there are indications that surface exposed antigens might induce a superior immune response, targeting of heterologous antigens to the OMV surface is of special interest.
Several recent preclinical studies in rodents have focused on the effects of DNA vaccines coding multiple TAAs, the authors hypothesise that delivering multiple TAAs will result in a wider and more potent immune response, targeting tumour cells with a synergistic effect [12].
Neither did the patient develop any response targeting the Y79F variant epitope as measured in samples obtained at weeks 88 and 139 (data not shown).
This could have an impact in the vector efficacy, as a balanced immune response targeting epitopes present in Env, Gag, Pol or Nef after vaccination will likely result in more effective inhibition of HIV-1 infection.
Similarly, with our model that explicitly takes into account a CTL response targeting infected cells during the intracellular eclipse phase, we can account for a strong suppression of virus replication during the chronic phase of infection.
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The dependent variable of interest was percentage of correct responses for each response targeted in the games.
According to a Libyan security official, Tuesday's attack, which triggered air strikes by armed forces in response, targeted Libya's government forces and allied fighters.
The response targets we set for fieldworkers were (approximately) achieved for LRAs, HIAs and PEs.
The most common cause of dry eye is an immune-mediated inflammatory response targeted against tears producing glands.
A response targeted to restore homoeostasis in the ER (endoplasmic reticulum), the UPR (unfolded protein response), is one of the best-studied cellular stress responses.
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