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Nor is this response restricted to humans.
A theoretical model and an experimental setup were specifically designed to identify and determine the delay of the cortical bone response (restricted to mineralization and demineralization) to a stress change.
Microinjection of aggregated A β42 into the brain elicited an inflammatory response restricted to the injection site of the wildtype mice, characterized by massive infiltration of microglia/macrophages.
This suggests that if a hyperinflammatory phenotype is a mechanistic intermediate linking accelerated periodontal destruction and diabetes, it is likely to be a localized inflammatory response restricted to the gingival tissues.
The concept of the T-B cell spreading phenomenon based on an initial acute autoimmune response restricted to a few epitopes using a limited number of T-cell clones for expansion is now widely accepted.
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To counteract virally-induced changes in the cellular metabolic profile, the interferon-regulated antiviral response restricts viral access to key metabolites by altering cellular metabolism, mediated through induction of specific microRNAs regulating key lipid biosynthetic processes.
It has been speculated that both fibrosis and the anti-inflammatory response restrict the arrival of new macrophages that are able to phagocytose the apoptotic bodies [46], thus allowing them to accumulate and favoring the mineralization process.
These data indicate that an early type I IFN-dependent innate immune response restricts the growth of Ptgs1/Ptgs2 −/− cells.
For example, pathogen-triggered immunity (PTI) constitutes the first layer of that response, restricting pathogen activity by blocking further colonization (Zhang et al., [ 70]).
These results indicate that rather than suppressing sFRP1 expression, β-catenin/TCF activity is associated with the induction of sFRP1, consistent with a feedback response restricting the exposure of a normal cell to a prolonged Wnt growth factor signal.
Our results indicate that CMV-specific cellular immune responses restricted by HLA-B*07 dominate those restricted by HLA-A*02 in both immunocompetent and immunocompromised individuals.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com