Sentence examples for response primarily to from inspiring English sources

17 CTLA-4 is thought to act in the early stages of an immune response, primarily to reduce T-cell responses to self antigens and prevent autoimmunity.

However, the FKBPs appear to have evolved to fill the ever-changing niches within these constantly evolving fungi, presumably in response primarily to the evolutionary pressure associated with the increase in the number of proteins that required chaperoning as the fungi increased in complexity.

Mice immunized with gD2 expressed from a viral vector mounted CTL responses primarily to one epitope located in the extracellular domain of gD2 (gD2245–259).

The teams constructed transmission chains during outbreak responses primarily to identify any previously unrecognized case-patients or contacts who might continue to transmit Ebola in the community or spread it to other areas of the country; use of these data for epidemiologic analyses was a secondary priority.

N2 animals infected with Orsay virus showed a robust secondary 22G siRNA response, primarily antisense to the viral genome.

Unlike with the induction of T-cell responses, priming and boosting with recombinant M. smegmatis did not induce anti-HIV-1 envelope antibody responses, due primarily to insufficient protein expression of the insert.

Data from the USA has shown a trend toward substantial increases in total non-response, primarily due to increased percentages of respondents who refused to be interviewed that was related to the level of urbanisation [ 42].

Time to progression (TTP), not radiographic response, was used as the clinical indicator for chemotherapy response, primarily because we wished to include patients who did not have quantifiable disease using standard imaging modalities.

The Ntr response primarily confers the ability to scavenge for alternative N sources, through the transcriptional activation of genes that encode transport systems and catabolic or biosynthetic operons by the global transcriptional regulator NtrC2.

IL-18 plays an important role in the TH1 response, primarily by its ability to induce IFN-γ production in T cells and natural killer cells [ 58].

We identified two tumours with similar growth characteristics but different RT responses primarily due to an antitumour immune response.