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Pleasure was found to be the best behavioral response predictor.
In the proposed method, a blind channel response predictor is designed to cope with the time variant channel.
Therefore, a major goal in RA treatment is to identify a reliable response predictor to anti-TNF alpha therapy.
In RA, previous studies using blood mononuclear cell isolates and microarray technology have been performed in the search for a response predictor to anti-TNF therapy [30], [31], [32].
Before building the response predictor, we sought to determine if the whole blood gene expression profiles at week 0 already clustered RA patients according to their response to anti-TNF alpha.
The rs12979860 SNP upstream of the IL28B gene was overall the strongest response predictor (p = 0.0001).
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Among other problems, Potti altered data sets to make drug response predictors look more accurate.
Response predictors need to be identified to define more targeted inclusion criteria and achieve precision medicine.
Clinical assessment for appropriateness of lithium treatment selection (i.e., response predictors) and close clinical monitoring may decrease the risk/benefit ratio.
First, she had clear response predictors (i.e., euphoric mood, absence of substance abuse, non-rapid cycling) with evidence of drug discontinuation three times with depressive episode recurrence, and, more notably, re-responsive illness with lithium reintroduction.
Several reports have used publicly available GEPs and in vitro drug response information from the NCI to develop drug-specific pharmacogenomics response predictors.
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