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They require the co-localization of adjuvants to induce, amplify, and guide an innate and subsequent adaptive immune response of sufficient magnitude and quality.
Another possibility is that the dose administered was not adequate to induce an immunological response of sufficient strength and type to be beneficial.
Therefore, the term immunocompetence may be defined as the ability of the host to launch an immune response of sufficient specificity and magnitude, and thus is a rough indication of the effective quality of the host's immune system [ 9, 10].
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Effective areas and responses of sufficient accuracy for proposal purposes can be found on the LETG Observer information page listed below.
Indeed, we and others have previously shown that the brain, particularly the hypothalamus, can sense ongoing immune responses (Besedovsky et al., 1983; Furukawa et al., 2004; for review see Besedovsky and del Rey, 1996) and, when the immune response is of sufficient magnitude, a neuro-endocrine immuno-regulatory "answer" is elicited.
One pig out of ten did not have a startle response, and three other pigs did not have a startle response of a sufficient magnitude to demonstrate the PPI seen in the other six pigs at the expected PP intervals of 60, 120, and 220 ms.
The present study was designed to evaluate whether or not these immunomodulatory responses were of sufficient magnitude to alter host resistances in a number of pathogen and tumor models.
Mice containing DC deficient in Opn-i produced excessive amounts of IL-27 and developed a delayed disease characterized by an enhanced Th1 response compared with the dominant Th17 response of Opn-sufficient mice.
Oral study 3 excluded patients who had failed to show minimal clinical response to sufficient doses of at least 3 different neuroleptics from 3 different chemical classes or to a dose of 400 mg/d of clozapine for at least 6 weeks.
WorldPost: Now that the Europeans have imposed stiffer sanctions, is the response of the West sufficient?
However, when CD8+ T cells initiate the inflammatory response in the abscense of sufficient CD4+ T cells to control the infection, a hyper-inflammatory response follows causing severe lung damage without reducing organism burden.
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