By doing this, Y. pestis actively avoids TLR4 recognition and the innate immune response necessary for the clearance.
Moreover, by binding to its receptors adenosine can initiate intracellular responses necessary for an appropriate voiding reflex [ 101].
That response, he said, was " a serious, considered answer" made necessary by promises to sources.
Performed using a series of steps: observation of behavior (score 1 or 2), followed (if necessary) by assessment of response to voice (score 3), followed (if necessary) by assessment of response to loud auditory stimulus or light glabellar tap (score 4 to 6) [35].
Performed using a series of steps: observation of behaviors (score +4 to 0), followed (if necessary) by assessment of response to voice (score -1 to -3), followed (if necessary) by assessment of response to physical stimulation such as shaking shoulder and then rubbing sternum if no response to shaking shoulder (score -4 to -5) [39].
Disordered thresholds can be resolved, where considered necessary, by collapsing adjacent response categories.
That response was necessary and driven by a sense of retributive fair play.
The PFKFB3 gene promoter contains hypoxic response elements necessary for transactivation by hypoxia-inducible factor-1 alpha (HIF-1α) in response to hypoxia [ 47].
Oakland's interim Police Chief, Howard Jordan, denied the use of rubber bullets (he said that "bean bag" rounds were used); he maintained that the police response was necessary because officers were bombarded by bottles, rocks, and paint.
One was the university's treatment of the sit-in protesters in 2013, which was regarded by some as heavy-handed and resulted in unfavourable publicity – though Farthing explains it as a necessary response by the security team (not himself) to criminal activity.
Often, SAPKs trigger the necessary response by directly regulating transcriptional initiation through phosphorylation of transcriptional regulatory proteins.
