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Side effects associated with these treatments and a poor response may require patients to terminate treatment (as did our two patients), making this condition very difficult to manage.
However, the practicality of design and the biology of the immune response may require that variable sites in multiple gene families are necessary as targets.
On the other hand a PPARA response may require an extended exposure, since DNA breathing with higher amplitudes is needed for the THz effect to take place via nonlinear resonances [18].
A plausible explanation for the fact that the RT-related signal appears to be much more reliable than the task-related signal is that the production of an overt motor response may require generation of highly synchronized and relatively strong impulses in corticospinal motor axons that are conveniently time-locked to the onset of the motor response.
Therefore, targeting cIAPs for controlling innate immune response may require additional concern to overcome the pseudo effects caused by caspase-11 passenger mutations.
Conclusions: These data suggest that DES-induced SV toxicity and feminization are primarily mediated by ERα; however, some aspects of androgen response may require the action of ERβ.
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Induction of more potent and durable responses may require new adjuvants or replicating chimeric vectors chimeras that bear HIV genes.
Additionally, RCC patients with different cytokine profiles and CEC responses may require different management.
These responses may require ATM or ATM-related protein kinase activity for the activation of cell cycle checkpoint factors; however, further investigation is required.
Alternatively, many cellular responses may require integration from multiple input pathways, and signal specificity could arise from this unique combination of pathways.
Senescence of the immune system makes the elderly more vulnerable to infections, and waning vaccine responses may require regular booster vaccinations.
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