Sentence examples for response machinery from inspiring English sources

It may encode a factor that is most likely a component of the central ABA response machinery.

Notably, we demonstrate that the central T-ALL oncogene NOTCH1 hijacks the cellular stress response machinery by inducing the expression of HSF1 and its downstream effectors.

At this point, the cell needs to mount a response to restore its homeostasis; however, the stress response machinery that it typically relies upon when faced with such challenges has lost its capacity to function.

He finished over twenty years later as a lieutenant colonel seconded to the Cabinet Office preparing intelligence briefings for Number 10, the Joint Intelligence Committee and COBRA Cabinet Office Briefing Room AA - the government's highest level crisis response machinery) where he was on duty on the night 11-12 September 2001. 11-12 September 2001

DNA damage induction (etoposide) in FUSwt and FUSmt MNs resulted in a similar increase of phospho-/total DNA-PK and cleaved /full-length PARP1 ratio (Fig. 7g, i, Supplementary Fig. 12) suggesting no major disturbance of the downstream DNA damage response machinery in FUSmts (Fig. 5d, e).

That is because the performance of our collective disaster response machinery is being tested amidst one of the most widespread, coordinated crackdowns on public employees in modern history.

These findings indicate that long-term evolution does not alter existing response machineries but rather adjusts gene expression homeostasis to adaptive steady states.

Inherited defects in human DNA damage response machineries (e.g., XPC, POLH, ATM) cause the faulty repair, damage tolerance, and checkpoints and commonly result in severe cancer predisposition disorders along with other different disease phenotypes.

Thus, a refinement of the cellular hypoxia-response machinery enabled cell stemness at oxic conditions and, then, animals to evolve into the oxic realm.

Here, we discovered that, in mouse testes, both spermatogonial populations possess intrinsic RA-response machinery and exhibit hallmarks of the differentiating transition following direct exposure to RA, including loss of SSC regenerative capacity.

Environmental stress often causes proteotoxic damage, which triggers the stress-response machinery in order to maintain cellular homeostasis.