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However, reporting bias may be present in the literature, and in order to evaluate if this response is applicable to all patients with C3G, controlled studies are needed.
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It should be noted that the tumor response model is applicable for all kinds of cancer radiotherapies.
The response is obtained directly from the elastic displacement response spectrum and is applicable to regular bridges with rigid superstructures that can be idealized as a single degree of freedom (SDOF) system.
The procedure uses the sequential frequency response technique, and is applicable if the situation remains stationary during the data acquisition.
The modal response spectrum analysis is applicable for all types of buildings, while the lateral force method of analysis has many restrictions on its use due to the 'fear' that it would provide un-conservative results in certain conditions; however, in spite of this disadvantage, the method is still widely used due to its ease of application (Crowley and Pinho 2010).
The response spectrum analysis is applicable for all types of buildings, while the lateral force method of analysis has many restrictions on its use due to the 'fear' that it would provide un-conservative results in certain conditions; however, in spite of this disadvantage the method is still widely used due to its ease of application (Crowley and Pinho 2010).
Similarly, pretreatment of these cells with palmitic acid compromised p21 and Bax induction and p53 phosphorylation (Fig. 5A and Supplemental Fig. S6A), suggesting that the function for SFAs in DNA damage response is also applicable to primary osteoblasts.
Furthermore, it could be that the association between CD11c expression and response is only applicable to patients receiving adalimumab monotherapy, as the signal was lost upon administration of concomitant MTX.
In the future, it will be of interest to determine whether the positive response to increased potassium levels is applicable to myopathies due to other RyR1 mutations and to other genetic causes.
At the end of the Discussion we have raised this important point: "In the future, it will be of interest to determine whether the positive response to increased potassium levels is applicable to myopathies due to other RyR1 mutations and to other genetic causes".
Future studies will be required to confirm these results and to determine whether our novel approach to develop an acquired resistance signature that predicts the therapeutic response of patients to specific chemotherapies is applicable to other types of cancer.
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