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We used [18F]-FDG-PET/CT to investigate the host response developing in nonhuman primates after MERS-CoV exposure and applied kinetic modeling to monitor the influx rate constant (K i ) in responsive lymphoid tissue.
Available clinical data indicate a lack of dose bronchodilatory response during initial treatment, with a dose response developing after ~1 2 weeks.
Collectively, the data demonstrate a local expansion of tumor-specific T cells with the CD4+ T-cell response developing more rapidly than the CD8+ T-cell response.
Indeed, whereas the LRP in the wake condition was rather transient and overlapped with the reaction times distribution, the LRP during sleep corresponded to a large and sustained response developing slowly over time.
Systemic inflammatory response developing post-CPB can be restricted to an extent of only a subclinical increase in the levels of inflammatory mediators or it can be severe enough to cause multiorgan dysfunction or even death [ 8].
Women with a history of emotional disturbance are at particular risk for a nonspecific depressive response developing later in the post-treatment period, while those who receive more extensive treatment are at risk for more acute, cancer-specific anxiety.
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It is, he suggests, "the response developed by the democratic West after a century of trauma in Europe".
As ideas about the immune response developed into the notion of an immune system, in the 1960s and 70s, the combat metaphors inherited from the previous century's germ theory acquired some new layers.
The standard answer to why we keep our nuclear bombs — a response developed during the cold war — is that we must have the capability to deter anyone who might attack us first.
As the arteries are minimally stressed, no trauma response develops, they say.
The adaptive immune response develops after the innate response and is particularly important in chronic infectious disease.
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