Sentence examples for response checkpoint from inspiring English sources

In a more recent study, Plk1 was implicated in a G2 DNA damage response checkpoint required for the stabilization of Claspin and dependent on the ubiquitin ligase APC/Ccdh and the phosphatase Cdc14B, a protein previously implicated in a later cell cycle control step during mitotic exit [35].

Loss of FHIT leads to alterations in the DNA damage response checkpoint, resulting in increased DNA instability [ 11].

Replicative senescence has been shown to be due to critically shortened (dysfunctional) telomeres activating the p53- dependent DNA damage response checkpoint.

Chk1 activity has been demonstrated to be critical for not only the DNA damage response checkpoint but also for replication fork stabilization, replication origin firing and homologous recombination.

To find out the nature of apoptosis induced by DPE plus UVA, we used mutant strains, such as DNA damage response checkpoint protein HUS-1 and the regulator CEP-1/p53.

mRNA expression levels were analyzed by means of quantitative real-time RT-PCR making use of a semi-customised PCR array, which enables the analysis of the mRNA expression of 94 genes coding for major proteins involved in DNA repair, DNA damage response, checkpoint control and cell death.

In response, checkpoints have sprung up on the roads into Daniyeh, unfamiliar cars arouse suspicion, and public buses have started to display signs kindly asking passengers to remove their jackets before boarding.

In response, checkpoints have sprung up on the roads into Dahiyeh, unfamiliar cars arouse suspicion, and public buses have started to display signs kindly asking passengers to remove their jackets before boarding.

VER-150548 at 1 µM did not inhibit MAPKAPK2, a kinase implicated as important in DNA damage response checkpoints.

Another DNA repair protein linking the DDR to autophagy is ATM, a DNA damage sensor orchestrating the cell cycle with damage response checkpoints and DNA repair to safeguard the integrity of the DNA.

We also added several further self-contained modules to the model (representing the spindle checkpoint, and the DNA damage-response checkpoint), which can be selectively incorporated into simulations.