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Menin has often been implicated in the DNA damage response and studies using Men1-/-MEFs have shown that these cells are hypersensitive to intrastrand crosslinking agents and fail to activate cellular checkpoints after γ-irradiation (γ-IR) [21], [22].
Viruses can evade the immune response, and studies of HIV-1 and SIV infections have shown selection of CTL escape variants during both primary and chronic infections [17] [20].
It is also feasible that the IL23R SNP could be used as a novel biomarker to predict therapeutic response and studies are currently ongoing to test this hypothesis in psoriasis.
Upregulation of cytochrome c transcript is a general early apoptotic response, and studies show that Hsp70 suppresses apoptosis by acting downstream of cytochrome c release in mammalian cells (24, 25).
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Ruan [32] proposed a diffusive plankton-nutrient interaction model with delayed nutrient recycling and delayed growth response and studied Turing instability and the existence of travelling wave solutions.
In [31], Cheng et al. established a pest control model with Holling type-I functional response and studied its existence and attractiveness of order-1 periodic solution.
This paper aims to build customer satisfaction constraints to restraint the demand response and study the impacts of the satisfaction indices on the optimal operation.
Another part of this study involved the use of response surface methodology (RS M and finding an applicable approximating function for predicting and determining the further response, and studying the optimum working state.
In [32], Tang et al. presented a semi-dynamic predator-prey model with Holling type-II functional response and studied the global stability of boundary order-1 limit cycle.
Response and study drug-related toxicities were evaluated according to WHO criteria (World Health Organization, 1979).
Revealing transcripts involved in immune response and studying their relative expression enhances the understanding of the immune response mechanism and consequently also the creation of vaccines.
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CEO of Professional Science Editing for Scientists @ prosciediting.com