The cortisol awakening response (CAR) has been used as a biomarker of stress response in a multitude of psychological investigations.
Besides the effect on genes involved in glutamate synthesis and transformation, the glu1-2 mutranscriptomeptome was characterised by an extensive secondary response including the downregulation of photosynthesis-related pathways and the induction of genes and pathways involved in the plant response to a multitude of stresses.
Positron emission tomography and computed tomography (PET/CT) based on a radio-labeled glucose analog known to accumulate in hypermetabolic cells (e.g., cancer cells), F-18-fluordeoxyglucose (FDG), is increasingly being employed in the diagnosis, staging, and evaluation of treatment response in a multitude of malignancies [3, 4].
Therefore, RNS-mediated inhibition of PhoPQ signaling may form an intrinsic component of the host response against a multitude of bacteria.
Bone is a phenotypically plastic tissue; it is capable of massive changes in size and shape in response to a multitude of influences within days to weeks [8], [52], [53].
The NLRP3-inflammasome is activated in response to a multitude of pro-inflammatory stimuli, including many pathogen-derived molecules, endogenous inducers of sterile inflammation, and non-pathogen microbial pore-forming toxins, including nigericin and maitotoxin [30], [31], [32], [33], [34], [35].
CREB is activated in response to a multitude of extracellular signals including growth factors, hormones and stress signals [ 42].
P53, P21Cip1 and pRb are well known regulators of both proliferation and apoptosis in response to a multitude of stresses.
In response to a multitude of stress conditions, HSF1 acquires DNA binding activity to the heat shock element, leading to the accumulation of Hsps (Wu, 1995; Morimoto, 1998).
