It was quite a big thing to talk about my family life and my experiences of coercive control, misogyny at work and the NHS, but I was humbled by the way readers responded, particularly to my piece about coercive control, which was shared 22,000 times.
The pSTS responds particularly to vocal stimuli [20], [21] and may be recruited specifically to monitor auditory feedback and to detect changes in specific auditory features, including vocal pitch [22] [24].
At the same time, it must be noted that antiapoptotic MCL-1 also seems to respond, particularly, to combined MG-132 and IP6 treatment.
BL1 and BL2 subtypes heavily express cell cycle and DNA damage response genes (ATR/BRCA), and representative cell lines respond particularly to anti-mitotic and DNA-damaging agents, such as platinum agents.
Prediction rules have been designed to identify patients responding particularly well to some non-pharmacological interventions [ 51, 52] and a community-based intervention has been developed to identify and target psychosocial risks in individual patients [ 53].
However, while LAMA, LABA or ICS + LABA combinations have been shown to relieve dyspnea, decrease exacerbations frequency and improve quality of life [ 2, 3], studies have been unable to clearly identify subgroups of subjects responding particularly well to a given medication [ 16- 20].
The results may also be influenced by GP recall and positive responding (particularly in regard to provision of a written asthma action plan by the intervention group); however, no statistically significant differences were found in the self reported provision of a written asthma action plan.
Tailoring treatment to a patient can therefore only mean assigning the patient to a certain sub-group of patients that appear to respond particularly well to a specific intervention.
Similarly, it would be of interest to genotype patients who respond particularly well to a given therapy to assess whether this relates to C9ORF72 gene status.
"Electors identified as switchers tend to respond particularly well to our policies on the energy bill freeze, reducing the starting rate of tax and increasing the top rate of tax".
