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The definition of responders varied between studies.
To our surprise, all of the α-helical coiled coil fragments were antigenic, though the prevalence of responders varied greatly (Tables 1 and S1).
The outcomes for suboptimal responders varied by time point.
The number of responders varied greatly during the study years.
The number of responders varied between questions and study years.
Responders varied in terms of how many messages they wanted and for how long they wanted the intervention to continue.
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Characteristics of non-responders vary with types of questions.
However, care should be taken when trying to make comparisons between trials, because doses, injection sites, and definitions of responder vary.
Our observation that the frequency of CD4 responders varies among the disease grades suggests that the CD4+ T-cell response might be critically involved in HPV clearance.
As a consequence, the criteria for dichotomising patients into responders and non-responders have varied considerably with respect to both the definition of response used, and the percentage reduction in the measured parameter that is deemed to represent a given response category.
However, while finding are consistent regarding long-term efficacy of therapy with no serious adverse events in responders, they varied in terms of durability of benefit, non-responder rates and the length and necessity of withdrawal of treatment at scheduled times [25, 43, 52, 58].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com