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Every patient was classified as a responder if he/she was accredited with, at least, a partial relief.
Each of the nine proposals asks the responder if they agree, disagree, or neither agree or disagree.
Those with less than three headache free days were only classed as a responder if they achieved a minimum of six headache free days after the treatment.
A child was considered to be a responder if, upon CS antigen whole blood stimulation, the frequency of CS-specific cytokine expressing T cells was greater than or equal to the geometric mean + 3 standard deviations of cytokine expressing T cells in unstimulated samples.
Specific anti-gSG6-P1 IgG levels were also assayed in non-Anopheles exposed individuals (n = 14 – neg; North of France) in order to quantify the non-specific background Ab level and to calculate the specific immune response threshold (TR): TR = mean (ΔDOneg)+3SD = 0.204, i.e. an exposed individual was classified as a responder if its ΔOD>0.204.
A patient was a responder if their IGA score decreased by ≥ 2 points from baseline.
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They can be first responders: if they called the genius of Patti Smith before she was Patti Smith, their taste in other new music is probably of note.
Patients were classified into three groups according to their CRP ratio: fast responders if CRP ratio was ≤0.4; slow responders if CRP ratio was >0.4 and ≤0.8; and non-responders if CRP ratio was >0.8.
We considered patients responders if they had > 50% reduction in headache frequency and/or pain intensity compared with baseline.
Subjects were classified as responders if their KOS score increased by ≥11 points [6] or if their pain score decreased by ≥2 points [7].
Patients were considered responders if they had a ≥ 50% decrease in number of headache days in at least two consecutive injection cycles.
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