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Of the CKD patients, the initial 25-OH vitamin D in the NON-RESPONDER group was lower than the RESPONDER group (18 vs. 23 ng/ml) (p = 0.03).
Among all patients, the initial eGFR in the RESPONDER group was significantly higher than the NON-RESPONDER group (36 vs. 30 ml/min/1.73 m) (p < 0.001).
The data suggests that the eGFR for the RESPONDER group stabilizes or increases over time, whereas the NON-RESPONDER group has a progressively worsening eGFR.
Baseline GTPase activity pathway was downregulated in the antidepressant responder group.
As a representative SNP, the frequency of G allele in rs9370435 in the responder group from the discovery set was lower than that in the non-responder group (0.37 vs 0.45).
As visible in Fig. 2E, the reduction of the leukemic burden is not as efficient in the poor responder group compared to the deep responder group, whereas the average initial NPM1 value does not differ.
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This was particularly true for the non-responder group.
There was no statistically significant difference in PET parameters of malignant lesions in the non-responder group.
As regards, the correlation between riboflavin efficacy and sex or age, we have found a significant prevalence of males in the intensity-responder group (P < 0.05), and of patients under 12 years in the frequency-responder group (P < 0.05).
Contrary to our preclinical studies, clinical results had limitations to evaluate malignant lesions in non-responder group.
As a result, loss to follow-up could decrease, especially in the non-responder group.
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