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Twenty-eight patients (90%) responded to induction chemotherapy.
The FACS analysis at single cell resolution indicates that all cells responded to induction, but not homogenously.
These patients had significantly lower rates of local recurrence and improved disease-specific survival than patients who responded to induction chemotherapy but did not undergo mastectomy.
It showed that ICERs of gemcitabine versus observation were more favorable in patients with PS = 0 or those who responded to induction compared to patients with PS = 1 or stabilization of disease after induction.
4 5 In the ACCENT II study (Crohn's Disease Clinical Study Evaluating Infliximab in a New Long-Term Treatment Regimen II), 36% of patients who had responded to induction therapy and received maintenance infliximab therapy maintained complete fistula closure compared with 19% of patients receiving placebo (p = 0.009).
Among negative specimens from previously treated patients, one was obtained from a patient in relapse after high-dose chemotherapy and ABMT, two were obtained from patients who had not responded to induction therapy, and six from patients in partial remission after induction therapy.
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The purpose of this study was to evaluate the efficacy of radiation-based locoregional therapy for locally advanced head and neck squamous cell carcinoma (LA-HNSCC) patients who did not respond to induction chemotherapy (IC).
In patients with refractory or recurrent follicular lymphoma responding to induction therapy with CHOP or rituximab + CHOP, maintenance treatment with rituximab compared to the "observation" option improves both overall survival and progression-free survival.
Resistive metals may be implanted in the plastic, which respond to induction heating.
Interestingly, the genes that fail to respond to induction conditions fall into two different subtypes: genes that are "not on" (Figure 6, clusters 1A, 2A,1B, 2B) in the mutants and genes that are "already on" (Figure 6, clusters 3A and 3B) in the mutants.
Failing to respond to (induction) therapy is another important determinant of progressive CKD and ESRD [ 27].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com