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Although clinical responses to abiraterone have been impressive, not all men respond, the duration of response is variable, and a majority eventually progress with a rising PSA.
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For the patients who responded, the duration of the response ranged from 62 to 287 days.
This indicates that the most characteristic BILAG domains, as also seen in Figure 2, were more likely to respond, although the duration of response was very similar throughout the domains.
The trpc5-KD mice reached the criteria by the first session and continued stable responding for the duration of the experiments, whereas WT took several days to catch up to KD responding.
In responding patients, the duration of the response to a single course of rituximab usually lasts more than 6 months 22 (category Ib).
Among those who responded, the overall median duration of response was 73.0 weeks (range; 9.0 136.4 weeks); median duration of response in group A was 77.1 weeks and in group B was 56.3 weeks.
Cows fed a ration with larger forage particles may respond by increasing the duration of eating and rumination or by increasing the number of chewing cycles per cud [ 26].
Among those who responded to ketamine, the duration of benefit varied widely, from 25 days to eight months, with the median 2.3 months.
Our patient may not have responded because of the duration and extent of the disease process prior to treatment.
Patients treated with bortezomib were assumed to have received between three and eight cycles of therapy while those in the comparator group were assumed to have received thalidomide for as long as they continued to respond (mean duration 6 months for responders and 2 months for nonresponders).
About 60% of ErbB2 patients do not respond to trastuzumab, and in those who do respond, median duration of response to monotherapy has been reported to range from 3.7 to 8.4 months (Norum et al. 2005).
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