Sentence examples for respiratory defect from inspiring English sources

Mice with homozygous knockout of mROR2 exhibit shortened limbs, cyanosis, septal defects of the heart and die within six hours of birth due to respiratory defect (Takeuchi et al., 2000).

We have further investigated the respiratory defect of Creb1−/− fetal mice during development.

It is also important to note that the respiratory defect in Creb1−/− mice is unlikely to be merely a secondary outcome of general developmental retardation or arrest.

In contrast, atg15Δ cells, which cannot perform the intravacuolar disintegration of autophagic bodies [23], inner membrane-bound structures of autophagosomes, exhibited significant respiratory defect (Figure 2C).

Instead, heterozygous mutation of dOpa1 leads to a respiratory defect in Complex II and III of the electron transport chain (ETC) as shown in our recent publication [23].

Instead, heterozygous mutation of dOpa1 leads to a respiratory defect in Complex II and III of the electron transport chain (ETC [23].

Interestingly, NKCC-1 gene knockout does not result in respiratory defects in mice [6].

After 120 hours nitrogen starvation atg mutants exhibit respiratory defects dramatically (WT: 3.8%, atg1Δ: 75.5%) (Figure 2B).

Sim1-/ and Sim2-/ mice die perinatally due to hypothalamic and respiratory defects, respectively [20], [21].

It is therefore plausible that the brainstem malformation caused by ATF2 mutation leads to similar respiratory defects to those seen in some forms of human sudden death syndromes.

While germ line deletion of Hoxb3 results in viable animals, Krox20 mutant offspring display significant respiratory defects and a large proportion die within hours after birth [44], [45].